Hacker News new | ask | show | jobs
by ghaff 3165 days ago
"Perfectly good" is an overstatement. Efficacy wasn't that great (80% or so) and there was some evidence of side effects. Overall, the vaccine should almost certainly have not been taken off the market but it's not a near-perfect vaccine vs. FUD story either.

See, for example: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/

2 comments

You may not need a higher efficacy, herd immunity does not require 100%.

Chart of herd immunity thresholds for some diseases:

https://www-tc.pbs.org/wgbh/nova/assets/img/herd-immunity/im...

oh_sigh is correct, humans are a dead end host for lyme. It's primarily maintained in a mouse reservoir - the larval and nymph ticks feed on infected mice, and then the nymph and adult ticks can expose humans and deer. Deer are not really a big reservoir either, since mostly adult ticks feed on them, but they do move ticks around.

Edit: you can actually try to vaccinate the reservoir, however: https://www.ncbi.nlm.nih.gov/pubmed/24523510

Lyme disease isn't passed from human to human so herd immunity is irrelevant.
My mistake, I thought it was a vaccine for the deer.
As I understand it the vector is mice, not deer. There's a correlation between mouse populations where the juveniles feed and Lyme disease outbreaks 2 years later when the adults latch onto humans.
lyme disease can be passed human to human as a std or the womb from mother to child
Lyme disease is NOT sexually transmitted. https://www.cdc.gov/lyme/faq/index.html
(citation needed)
> Overall, the vaccine should almost certainly have not been taken off the market

It's no longer patented so nothing is stopping you from selling it if you think there's a market.

Read "should not" as it's unfortunate that potential legal issues around Lymerix were such that a vaccine was a losing business proposition. In general, human vaccines aren't a great opportunity for pharma companies--to the point where they're protected against liability for common vaccines.