The OSD335x-SM uses the same power management solution as the BBB. The chip itself will consume less power than the BBB since it doesn't have all the additional peripherals.
We currently have stock as DigiKey and Mouser and will maintain stock. If you have additional questions on supply, feel free to contact us (https://octavosystems.com/contact/)
There are still some issues around RTC. The PMIC that we use (TPS65217C) doesn't support RTC-only mode, so unfortunately, you will still probably want to use the discrete RTC to get the standby time you need.
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Thanks for the responses Eric!