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by gus_massa
3208 days ago
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The mutation rate of mitochondrial DNA is much faster than in nuclear DNA [1]. But mitochondrial DNA does not have crossover, so the mutation tree is much easier to build. [1] From: https://en.wikipedia.org/wiki/Mutation_rate#Variation_in_mut... > Human mitochondrial DNA has been estimated to have mutation rates of ~3× or ~2.7×10−5 per base per 20 year generation (depending on the method of estimation); these rates are considered to be significantly higher than rates of human genomic mutation at ~2.5×10−8 per base per generation. Using data available from whole genome sequencing, the human genome mutation rate is similarly estimated to be ~1.1×10−8 per site per generation. |
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