[carbocation]

> it's possible that the brain fog is coming from the CRP and other stuff that's getting released as your muscles break down

CRP is not released by muscle breakdown. It is a predominantly liver-produced acute-phase reactant that is an inflammatory marker. Myoglobin, on the other hand, is released by muscle breakdown, but this is only appreciably released in severe circumstances such as a crush injury. The major harm of myoglobin is to the kidneys, not the brain, and I'm quite certain that CBD does not help this.

>CBD is non-psychoactive and doesn't even act in the brain

CBD acts in the brain.

[Alex3917]

Thanks for correcting the science. My more general point though was that chronic low-level inflammation causes a large percentage of depression / brain fog type things, and CBD can help with this:

http://www.google.com/search?sourceid=chrome&ie=UTF-8&#3...

And depression/anxiety causes inflammation too, so you really have to break the feedback cycle.

[metamemetics]

A great anti-inflammatory supplement besides cannabis is Turmeric due to its high Curcumin content.

http://en.wikipedia.org/wiki/Curcumin

In vitro and animal studies have suggested that curcumin may have antitumor,[9][10] antioxidant, antiarthritic, anti-amyloid, anti-ischemic[11], and anti-inflammatory properties.[12]

[Alex3917]

Thanks for pointing that out, I didn't know that.

[carbocation]

Interesting; I've never heard that before. Do you mean that there is peripheral inflammation and the cytokines pass through the blood-brain-barrier, or do you mean that there are actually inflammatory cells that enter the brain and cause depression? Also, can you cite something more specific than a Google search? Most of those are for-profit or interest group websites.

Edit: I found an NIH reference: http://www.nimh.nih.gov/science-news/2009/key-molecule-in-in...

Of the two options I mentioned, it's the former (peripheral inflammation with release of cytokines). Thanks for sharing.

[Alex3917]

Yeah, if you Google for cytokine theory of depression there are a bunch of papers. I'm not an MDPhD so I have a very limited understanding of the science, but from observation and personal experience the hypothesis seems quite accurate. The good news is that it's extremely easy to manage, the bad news is that no one knows this.