(On the off-chance you're not being tounge in cheek): No, "used positively and negatively with the same meaning", as in the two differently phrased idioms mean the same thing:
To be perfectly honest, I'm kind of 50/50 between a genuine vexation with "could care less" being semantically wrong, and a cheerful agreement that usage defines meaning. The world's inconsistent and so occasionally, in response, am I. :P
> people who say “I could care less” are omitting the first part: “Like I could care less,” [Slate link]
These quotes seem to sum up those links.