[smitjel]

No, that strictly depends on how you've designed your site. To have your site look the best in ALL browsers, make subtle use of CSS3 effects. Don't _rely_ on them. If you follow that, you won't be writing off "50%" of your users design-wise.

[compay]

Sure, but then you're writing off CSS3 and continuing to write code as if it were 2006, which I personally don't like having to do.