[ealloc]

"Single Particle Reconstruction" for Cryo-EM reconstruction algorithm, anyone?

SPR is an algorithm already used to reconstruct 3d objects from a set of 2d images produced by an electron microscope, typically of a protein on a flat surface.

I haven't read the paper here, but I suspect a key part of the algorithm is that it can only reconstruct objects with symmetry planes: The airplane, chair, car are all symmetric across an axis. This greatly constrains the possibilities the algorithm has to search through. In em-reconstruction the user often specifies what they think the symmetries are beforehand.