[rtpg]

It's not a dealkiller for most things, but imagine the opposite:

What if startup time for python scripts were 0.1ms? In this case you could imagine writing throwaway scripts and just spawning a new process every time you wanted a result. No need to build a shell to (say) hold onto a DB connection or things like that. Just write the core business logic.

That being said, for the most part, I/O is more than 35ms.

If you have a "serious" Python program, though, you easily enter seconds-long-startup from dependencies. There's some libraries that do not pay a lot of attention to this and mean things like web servers a bit more frustrating. You can no longer spin up a server when the request comes in, but must do it before.