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by reasonattlm 3230 days ago
Mutations are stochastic.

Pick a hundred cell lineages from skin samples, and merge back to the common root genome minus the stochastic mutations in their ancestors. Then apply CRISPR or some selection technique to the skin sample you've converted to iPSCs to obtain the genome you want. Most of that could be done with today's technology, were anyone so inclined.

Twenty years from now this will be an afternoon intro project on one of the lab machines in CellBio 101.