I second this, if you can tolerate the Midwest winters.
Kansas City has plenty of industry (and great BBQ!) and is fairly clean. One downside is the lack of a light rail system.
The winters aren't too bad and I'd say pretty mild actually. You get more ice storms than snow in KC. It's not like Chicago or Minneapolis by any means. Lightrail expansion is coming in the next few years, which I think will officially take it out of the "toy project" state it is in now. I also think with the addition of the new airport KC will just blow up. It's already growing pretty rapidly.