Between Raleigh and Durham, it's mostly sister-sites for larger tech companies. Personally, I've worked at NetApp, Citrix, and now Nutanix -- all within 25 minutes of my house in Cary.
There are a handful of co-working spaces that house startups around American Tobacco Campus in Durham and Downtown Raleigh. There's not much VC in the Raleigh/Durham area though so most are bootstrapped by founders.