[tzs]

If a coworker says "Our app is huge, like my dick", I'd say that gives his implicit consent for others to use his dick for comparisons, at least for a while:

"The bug was just a small one, like <coworker>'s dick".

"We missed processing the event because it came too soon, like <coworker>'s dick".

"Dammit...I need to reset this router and don't have a pin to poke the reset hole. <Coworker>, can you use your dick to do it for me?"

Being the butt of dick jokes for a week (especially if some of these making them are women) will probably strongly discourage <coworker> from making future comparisons to his own dick.

[flukus]

This used to be acceptable in many smaller places, even ones with women because it was a much harder burn coming from them. These days you have to just go to work and avoided any sort of socializing or non-work related discussion, keep work life and social life completely segregated and hope that's enough (it isn't always). This is the world political correctness (or professionalism if you prefer) has created.

Best to avoid eye contact too, someone could misinterpret that as flirting.

[tyrw]

This is a truly terrible idea