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by Real_S 3247 days ago
Thank you for clearly sharing how and why scientists can accurately measure genetic effects in twin studies. You are correct in your assertion that mono vs di - zygotic twin studies are usually good measures of heritability.

I would add a slight technical caveat. Twin studies are excellent at measuring additive genetic effects, i.e. when different genes add together nicely to contribute to a trait (height is a good example). Twin studies typically assume that genes do not interact in funny ways (e.g. epistasis). Thankfully, for many, but not all, traits examined the additive genetic effect catches most of the heritability.

If epistatic interactions drive a trait, however, the statistical models typically used in twin studies would actually under-estimate the influence of genetics.

Further reading: http://www.apa.org/monitor/apr04/second.aspx