Sure. But in practice everyone is just going to make extensions that are compatible with "all" the browsers, and there are developers who have simply decided not to rewrite their firefox extensions.
There's a Tree Style Tabs-like WebExtension. It has a few quirks, though. It runs in the sidebar. It doesn't hide the top tabs (though you can do this with Stylish). It has its own menu for tabs which does not include some options (like send tab to device).
There was a very good non-nested side-tabs extension in Firefox Test Pilot, but it has expired.
http://fasezero.com/lastnotice.html