[nine_k]

Do you want a secession? Because this is how you can get things to a secession. The law of the land applies to everyone, and the only way to have a law applicable equally to two groups with conflicting interests is to force one or both of them to sometimes do things they don't want.

A half-way solution is a confederation, Switzerland-style. Weak central government, large variation in laws between cantons. Good luck trying to pull power back from a central government, and make people of California agree that people of Alabama should be allowed to live according to their [add derogatory terms] principles, and vice versa.

[AdrianB1]

A possible solution is to reduce the surface of what can be imposed by law, so that what people vote can affect less the people around them. This can be done by more and stronger liberties (not rights, that's a different story). But even this one is far from enough. I am not thinking of any secession, that would solve nothing.

[nine_k]

You want fewer things regulated by law? It's a fail goal, but you will face a huge number of "think of the children (elderly, environment, etc)" type of legislation, completely well-intentioned.

One of the problems with democracy is that governing a state is a job that should require certain qualification, experience, etc, but voting does not require any of this. Presumably the elected officials should be the experienced, reasonable people good at governing the state and making the least harmful compromises. But it's only a presumption. (Authoritarian governments are usually no better in this regard, too.)