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by msie 3274 days ago
Any human trials yet?
1 comments

Unity will be starting human trials this year, so far as we know.

Oisin will follow later this year or in 2018, if they keep to the standard way in which things work in biotech companies following an A round.

I have no idea what SIWA will be doing; they have been around on life support for a while, and now resurrected by the newfound money coming into the field. I'd imagine that their next step would be some form of trial, though it is unclear as to where exactly they are in their animal study schedule.

There are people self-experimenting with senolytic drug candidates now, though not in any way that will provide useful data. If you draw the line at candidates for which there is in vivo evidence in mammals, you're left with just the chemotherapeutics and foxo4-dri. (A pity that fisetin has no in vivo evidence yet...). The chemotherapeutics are worth skipping over, since they are ugly chemicals and really only a starting point for the development of analogs without the horrible side-effects, and foxo4-dri hasn't been tested in any formal way in humans yet.

At the pace at which new drug candidates are emerging and being tested, a couple of years from now would be a good time to be self-experimenting.