In many southern tech cities corning someone and yelling at/assaulting them with unknown fluids is a great way to get shot. We recently hired a CA transplant to the dev team and he was shocked how many of us carried.
If I'm cornered by a crazy man who's shouting and dousing me - if it hits me in the face, quite literally inoculating me - with God knows what? Even here in duty-to-retreat Baltimore, you'd have a hard time calling that other than self-defense.