[corysama]

AFAICT, there are 2 major differences between Nix and Guix. Language choice is the obvious one. The other is that Guix takes a hard-line stance on the GNU philosophy and therefore refuses to distribute pre-compiled binaries. I don't think CUDA will ever be an option on Guix.

[geokon]

Pretty sure there is nothing language-wise stopping anyone from hosting a separate repository with pre-compiled binaries.

It's a volunteer-run service. It makes sense they don't want to host your proprietary binaries