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by Darvict 3307 days ago
https://en.m.wikipedia.org/wiki/Suramin

Things to note:

- Administered solely by injection.

- Not FDA approved.

1 comments

For those of you who read the side effects on the Wikipedia page, the article addresses 'em:

> Unlike treatment for African sleeping sickness, which involves multiple, higher doses of suramin over a period of time and frequently results in a number of adverse side effects ranging from nausea and diarrhea to low blood pressure and kidney problems, researchers said the single, low dose of suramin used in the ASD trial produced no serious side effects beyond a passing skin rash.

> It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet.

That's an intriguing symptom, given that many inflammatory/autoimmune conditions cause peripheral neuropathy. I wonder if what is being described is the "unblocking" of peripheral nerves, causing a flood of signal-distorting noise as they re-join the nervous system.