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by frandroid 3304 days ago
What are the chances that a specific mutation exists once you modify more than 4 or 5 bits of DNA? It's like 1 / (number of base pairs ^ 4) or something. The chances are almost nil.
1 comments

That isn't how NHEJ works. All they see is some random indel at the site. So all you have to explain is the presence of any mutation at the target site.