[awjr]

Tragically things like Dementia and Alzheimers can do this. Also numerous mental conditions e.g. depression, stress, etc.

I knew one guy that got a degree in Comp Sci and in his first job began getting severe debilitating headaches. He was diagnosed with a visual problem and was told to stop using screens in his day to day job. He quit a promising career as a software engineer and went and joined his dad's gardening business.