[tuna-piano]

While the math isn't exactly right - even if Alexion returned all profits to its patients at the end of the year, the cost of the drug would still be only 20% less than the current price. So instead of $500k, it would be $400k. Would that really change the dynamics of the discussion?

[refurb]

Great point to call out. Also, Alexion uses about 21% of their revenue for R&D. So of the $500K they sell the product for, $100K is profit, $100K goes back into R&D and the rest is paying for expenses.