[a_imho]

Can we crispr resistant bacteria to be susceptible to penicillin/antibiotics again?

[ccozan]

Interesting idea. So you would first infect voluntarily with a custom virus that targets the bacteria by using CRISPR to remove the DNA strand of the resistance, then simply use the usual antibiotics to kill it.

[mathw]

At that point couldn't you just make a custom virus which kills the bacteria, so it happens in one step?