[ChuckMcM]

Depends on the size of your data set. Intel's plan, according to their web site, is to replace the SSDs (especially NVME ones) with Optane based solid state memory. The road map has them shipping exabytes of the stuff eventually.

So as I see it you'd be constrained by 32GB Optane modules today, but they will eventually (one, maybe 2 years) be 2 TB modules like the Samsung 960 Pro modules are today. And an M.2 port is really just a PCIe slot so you're looking at systems with maybe 32 TB of Optane storage on the high end within the next 5 years.