Ubuntu 16.04 or Fedora are likely to work better than 17.04. Regardless there is still hardware that does not have the best compatibility. Ubuntu does handle individual high DPI displays well though.
I've got the new line of radeon graphics card. 16.04 only supported some <1080p resolution, 16.10 supported 1080 and 1080p landed in 17.04. Red hat was a similar story. HDMI sound doesn't work with any of them.
It was quite frustrating to read about ATI's new open source drivers, purchase that hardware explicitly because of that and still have it not work, but it's nice that it's improved so much too.
Ahh... yeah it is still easy to fall in the cracks. When you get a good system and everything works it is beautiful, when it doesn't, you will be spending quality time with kernel parameters and resources like the Arch Linux wiki. I had a miserable time troubleshooting i915 on my Dell XPS 13" (latest edition). Very frustrating to have an officially supported Dell laptop with Ubuntu that doesn't even work right out of the box.
It was quite frustrating to read about ATI's new open source drivers, purchase that hardware explicitly because of that and still have it not work, but it's nice that it's improved so much too.