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by kregasaurusrex 3361 days ago
Is there a list of genetic services and what data they provide somewhere, maybe a comparison of sorts? My father recently passed away of arryhtmia and I'm looking for a way to determine if said condition is hereditary or not.
2 comments

If you have concerns about a specific trait in your family history, I would suggest speaking to a genetic counselor. Many genetic conditions are influenced by a suite of relatively rare mutations not commonly included in commercial kits. A geneticist can tell you if this condition localizes to a specific chromosomal region or set of regions and sequence those target regions in depth for a better estimate of your risk profile. Perhaps more importantly, they can tell you if it is worthwhile to do so. Some conditions are too complex to reduce to effective testing, or result from poorly-characterized private mutations, but may have associated non-genetic biomarkers that your physician can monitor if you bring the problem to his attention. If your father's condition was well characterized and you have access to his history, you can do preliminary research on SNPedia (SNPedia lists whether a SNP of interest is included in the 23andMe kit), or do a PubMed search on "genetic risk factors" /"targeted next-generation sequencing" $condition to get a sense of the state of the art.
Look on Promethease wiki and Reddit.