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by Kequc 3361 days ago
When I signed up the sample they took was spit in a vial.

It never clicked for me that this was going to be the most scientifically accurate reading of my health in all the world. I took part because it could give me some scaring and soothing. But I assumed I'd go get a real test done if I was actually worried or interested about something specifically.

The website repeats this sentiment over and over, I learned about all kinds of interesting genetic stuff. I'm sure that's what it's for. I shouldn't be surprised that many people take what it says as gospel.

3 comments

The "real" genetic test I took in doctor's office to screen for a condition worked by spitting in a bottle too. It's a reasonable way to collect DNA.
> I learned about all kinds of interesting genetic stuff

And there's much more to be found. The service of 23andme only records a limited set of SNPs. Further there is "multiomics" (see [1]), where not just the genome is sequenced but a complete biological fingerprint of metabolites is taken at different timepoints. This can e.g. give insight in onset of a disease even before any symptoms present themselves. I wonder when this will become available as a (mainstream) service, but I guess soon.

[1] https://en.wikipedia.org/wiki/Multiomics

> When I signed up the sample they took was spit in a vial.

Yes, and? I don't see the significance of the testing medium here. DNA sequencing from hair or blood or saliva will yield identical results.

They're saying the testing medium itself made the test appear less scientific/accurate (to them) than it actually is. Perhaps if it had been a hair sample it would have appeared more scientific (again, to them).
Yes that's right.
Yup and in both sources, it will be multiplied first via polymerase chain reaction, and then analyzed / sequenced.