[majewsky]

Come to think of it, it's pretty ironic. For years, admins have been told to move static content to a different domain to trim down the request size (since browsers won't include the cookies for the main site). Now that might reverse, and it might be best to send all HTTP requests to the same server (for large sites: most likely some load balancer or haproxy or whatever) in order to benefit from HTTP/2 multiplexing.

[valarauca1]

HTTP/2 really seems more like a front end balancing and caching protocol.

Handle your TLS/HTTP2 termination on the same boxes and use HTTP1.1 within the internal network.