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by apl 3391 days ago
Even in these apparently simple feedforward sensory networks, connectomics haven't been the anticipated panacea. There's been a flurry of follow-up papers to Takemura et al., essentially refuting the suggested model.

Turns out, even where they should connections don't constrain circuits to a sufficient degree.

1 comments

Awesome, do you have a good cite for that? The last time I paid attention in this space was a year+ ago, when the vision people were trumpeting these results, so I'd love to know more about the current thinking. It's been my go-to example for "connectomics will help with some things", but I'm not a sensory physiologist.
Try this: https://www.ncbi.nlm.nih.gov/pubmed/26234212

I guess the key lesson is -- don't rely on a single approach, because its limitations may well lead you astray. Applies to connectomics, physiology, modelling, etc.