[cesarb]

> All GUI code I've seen relies on inheritance and dynamic dispatch to structure APIs.

Rust has dynamic dispatch, by using trait objects (https://doc.rust-lang.org/book/trait-objects.html). It also has something similar to interface inheritance ("trait Foo: Bar" means that everything that implements the trait Foo must also implement the trait Bar), and one can always do "C-style inheritance" (have the parent be the first field of the child) for structs.

Given that, I'd say building a large, complex GUI framework in Rust is possible. I also wonder how a GUI framework written for Rust (instead of Rust bindings to a framework for another language) would look like.