That's vague. AWS also powers huge websites and Amazon is recommending Aurora as the "default choice" for most workloads.[1] There are certainly significant architectural differences but I would say we can definitely make a direct practical comparison.
And their needs are reasonably complex. They use machine learning and big data analytics to generate the list of videos that you should be watching. In order for those to work they need to capture a whole raft of end user metrics e.g. at what point you paused video X.