[Dan_Nguyen]

Regarding longevity, it's also worth noting that telomere shortening are a very effective anti cancer mechanism.

Cancer is the runway division of cells. Preventing cell division when the telomeres are too short ensures there is a finite number of times a cell can divide, meaning there is a finite number of times a cancer cell can divide. This helps prevent cancer from dividing indefinitely. Especially in older folks, we see how terrible cancer can be when those cells mutate and can regenerate telomere length, giving themselves unlimited division.

It's the physical trade-off we have with lengthening or preserving telomere length. They give all of our cells more divisions, good and bad. Since cancer is an exercise in the law of large numbers (how many random mutations will it take for it to hit a critical point in your DNA?), Longer lifespans with longer telomeres will inevitable also mean more aggressive cancers.