Nope, but I run it at 100% scaling. I did notice that if the source on the TV is not labeled "PC" then the Mac uses YCbCr 4:2:0 and looks like garbage. Setting the input label to PC must send a different EDID because it seems to use RGB... On my Windows machine I can just override that in the nvidia control panel.
https://support.apple.com/en-us/HT206587