> we know that once surplus white adipose tissue is grown, there's no going back, a modified diet must be adapted for life or those buckets just start filling again
Mind providing more references/reliable pointers on this?
Paper on WAT quantity and its effects on metabolic syndrome. http://onlinelibrary.wiley.com/doi/10.1111/eci.12519/pdf . Where this one gets me thinking is that for some people, growing WAT may actually be an adaptation to prevent metabolic disorder from a poor diet.
What we know is WAT can hold about 4x its size in fat before it divides into more. What we don't really know for humans is whether long term weight loss allows us to lose some of these, or whether they just deflate.... some rat studies show there can be a reduction, but for humans it would require repeated biopsy......
Paper to get you thinking on how WAT acts on signaling: http://www.cambridge.org.secure.sci-hub.bz/core/journals/pro...
Paper on WAT quantity and its effects on metabolic syndrome. http://onlinelibrary.wiley.com/doi/10.1111/eci.12519/pdf . Where this one gets me thinking is that for some people, growing WAT may actually be an adaptation to prevent metabolic disorder from a poor diet.
What we know is WAT can hold about 4x its size in fat before it divides into more. What we don't really know for humans is whether long term weight loss allows us to lose some of these, or whether they just deflate.... some rat studies show there can be a reduction, but for humans it would require repeated biopsy......