[spaceheeder]

To my knowledge no such report exists. The only answers you'll find will come from reading dozens of articles like this one over a long span of time, mixed with reading "primary sources" (put in quotes because as often as not those sources may be trying to sell you something).

While I am not qualified to put together a comprehensive report, I've been following this subject with some interest for a while, first as a skeptic, and now as someone who believes that not all of these people are completely full of hot air.

Even with my change of heart, I'd still bet against anything in your list other than crispr having any quantifiable impact on longevity in the next decade, and even then the first applications will be specific to particular age-related diseases.

Something resembling a more full "maintenance approach" to preventing aging and age-related disease may be within reach within 20 years, but I'd bet against that, too. Sticking my finger in the air and guessing, I'd say that such a complete overhaul of medicine is at least 50 years away. Although I should stipulate my guess is only that pessimistic because I'm biased towards thinking that such advances won't be made in my own lifetime because, hey, it rarely hurts to be a pessimist.

[AstralStorm]

The main problem now is delivery of such gene therapies. Crispr is pretty limited.

And human in vitro modification is taboo also wrapped in politics.