[WalterSear]

Pharma can't make money on comoditized, public domain medicine. The alcohol industry doesn't have a relevant infrastructure or supply chain. Tobacco is the only industry that's in a position to pivot, but the profit margins on mass cannabis are much less than tobacco, since it consumption is inherently lower. That said, Philip Morris purchased a few hundred thousand acres of Humboldt county in the early ninties, in anticipation of legalization.