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by tgokh
3470 days ago
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Sounds like (from the Italian article) she had already had an unsuccessful (or attempted?) kidney transplant in 2014. The patient appears to have some sort of vascular as well as immunological issues (again, my broken translation from the Italian). When the donor kidney isn't a blood-type match for the recipient, I believe you can do the transplant with a splenectomy and plasmapheresis to eliminate pools of immune cells and desensitize the immune response to the incompatibility, but I believe that splenectomy has largely been replaced by treatment with rituximab (antibody-drug that targets immune B cells). Perhaps the combination of congenital vascular issues plus incompatibility in this patient made the transplant + splenectomy approach preferable? |
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The child is 6. She's needed dialysis since she was born. She never drank water, to prevent problems.
There was an unsuccessful transplant in 2014, because of the immune response.
They couldn't risk another transplant using the blood vessels of the kidneys. She was also at risk of not being able to keep doing dialysis because of the problems to those blood vessels. Because of all of that, they decided to remove the spleen and use its blood vessels for the new kidney. She urinates normally now and she can drink water.
I couldn't find information about the issues with the blood-type mismatch.
[1] http://torino.repubblica.it/cronaca/2016/12/14/news/torino_t...