So far, for the use-cases I can think of, it's probably not worth it. Serialization and thread overhead outweigh any benefit. There are definitely better use-cases for workers than VDOM.
Some of the other uses typically are - sort of flow control between the thread and the worker, so that only sufficient VDOM operations are sent across the thread.
This basically leaves the UI thread to other things like GIF animations, redraw UI like buttons when user interacts with them, etc.