[samfisher83]

Do they use ITA as their back end software?

[benjaminRRR]

SkyScanner is not an agency, they use other players to provide the content and fulfil the product so they'd have no use for ITA.

[diakritikal]

My understanding is there's a heavy amount of scraping involved.

[Torn]

Nope, it's currently a meta-search that owns its own data layer. As to what the future will bring let's see!