[grayrest]

The only use case for jQuery is if you want virtually all your logic and rendering to be server side and only want to use javascript for toggles, form checking, or other jQuery sprinkles. I wouldn't choose this but if someone did and picked jQuery I wouldn't question the jQuery part much.

If you're writing more than a couple hundred lines of javascript, the jQuery model of putting your application state in the DOM is inferior to pretty much any other application model. There's a reason everybody went to Backbone and then to the component libraries. Separating your model and rendering concerns and delegating the latter to your framework roughly halves the amount of code you need to write.

[city41]

Not to mention storing app state directly in the DOM can have performance implications, as JS needs to cross the bridge and possibly force relayouts to access the state info.