There's a fantastic, massively upvoted StackOverflow post that can also provide some insight here. This may be a little more accessible, since it's such a significant runtime difference with very simple source code.
For those, like me, that want to play with what this stackoverflow talks about, here's a fiddle of it: https://jsfiddle.net/tbinetruy/Latkmk2q/1/ (code takes 2s to run and loads firebug for console logs).
http://stackoverflow.com/questions/11227809/why-is-it-faster...