[k__]

Not a Python dev, so I don't know about that.

But could you elaborate on the "Nix-env conflicting with system profile" thing? :)

[atemerev]

This, for example: https://github.com/NixOS/nixpkgs/issues/18778

I support the idea of declarative configuration and dependencies, but I also realize that this is a very very hard thing to do, when each language have its own preferred package manager and they all expect a mutable environment.

(I tried NixOS for 2 months and switched back to Ubuntu. The issues are too numerous so far, despite heroic work of NixOS dev team)