Hacker News new | ask | show | jobs
by HarryHirsch 3505 days ago
Us chemists use retrosynthesis to disconnect the target cpd into accessible fragments of appropiate polarity that can be conveniently joined (that's three issues in one), and consider electron flow (i.e. arrow pushing) to think about what reactions would proceed smoothly.

Manipulation of 2D-connectivity, as seen in the paper is new and not for humans.