[scott_s]

Sometimes, the techniques you use to scale to 100s of threads solve some NUMA issues by virtue of the fact that in order to scale that high, you need to avoid touching as much non-local data as possible. I think it's better to just deal with the pain now and start running your experiments on as large of a machine you can get access to. You can still put off explicitly designing for NUMA, but you want to avoid spending too much time and effort designing for the lower end of the scalability spectrum.