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by catscratch 3542 days ago
I liked Vyvanse more than Evekeo. I had much less depression, was much more motivated and able to focus during the day as well as evening, and I still could get to bed easily and sleep well-enough. But, I acted too hyper on it.

Perhaps I could try to practice more self-control and continue taking it or could try taking 1/2 the dose, but after I had problems, my doc put me on Evekeo. I take one in the morning and mid-day, and I'm much more even-keeled than on Vyvanse. The downside is that it's not time-released. I have ups and downs and my brain is not working as well in the evening like Vyvanse. I also don't get sleepy as much at night when I should. But, it's much, much better and safer for me than not taking anything. I might start taking a low dose of Zenzedi in the afternoon to see if that helps problems getting to sleep.

Evekeo is 50/50 dextroamphetamine/levoamphetamine; in some sources it's just called amphetamine sulfate, but the ratio is important.

Zenzedi is also made by Arbor Pharmaceuticals and is pure dextroamphetamine sulfate (which is the really addictive one).

Adderall/Adderall XR is 75 percent dextroamphetamine (the regular Adderall is a mixture of dextro salts in that 75 percent) and 25 percent levoamphetamine.

In comparison, Vyvanse is the prodrug lisdexamfetamine that is converted to dextroamphetamine and lysine by the hydrolytic activity of red blood cells, so it's time-released.

I'm told the levo form is for increased wakefulness and improved focus and dextro is for energy and speeding up executive function. I don't know if it's really that simple, but that seems to mirror my experience.