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by Hydraulix989 3552 days ago
Remember though, NP complete problems still are intractable (exponential complexity) even for quantum computers, to say nothing of NP hard.

Unger and Moult (1993) have shown a three-dimensional protein folding model to be NP-complete, and a two- and three-dimensional mathematical model describing the folding process as a free energy minimization problem is NP-hard:

https://www.gwern.net/docs/1993-fraenkel.pdf