[namewithhe1d]

How about taking a look at the voice talent to understand why the characters are largely male dominated? Dan Castellaneta, Hank Azaria and Harry Shearer account for the largest majority of characters on the show. They have incredible flexibility and range. Nancy Cartwright voices Bart (not accounted for in the male/female numbers) and several other male characters, and thus expands the male repertoire. Yeardley Smith (Lisa) and Julie Kavner (Marge) have pretty distinct voices, and while incredibly talented, don't contribute many more characters to the show outside of "soundalikes" like Marge's sisters, etc.