[wdewind]

"Shaman/Medicine men have been having visions for years and using substances to get closer to nature since humankind started - agree with your point about "rediscovery"."

So have completely insane people. If only we had some way to tell when people were full of shit...oh wait, thanks science!

[rosser]

In the case of most pharmaceuticals, the best science can tell us is that this chemical correlates with that effect. We still don't know how aspirin does what it does for chrissake -- just that it does it. The only difference between that and a shaman is clinical trials. (Except, of course, that the shaman actually has an explanation for how his medicine works, however anathema it may be to the traditional Western mindset.)

[nollidge]

> We still don't know how aspirin does what it does for chrissake

http://en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

> The only difference between that and a shaman is clinical trials.

Yeah, man, totally. Well, that and safe dosage, drug interactions, toxicity profile, half-life, chemical formula, side-effects...

> Except, of course, that the shaman actually has an explanation for how his medicine works

This merely proves that anyone anywhere can invent a just-so story.

[rosser]

re: the MoA of aspirin, I stand corrected; thank you.

Yeah, man, totally. Well, that and safe dosage, drug interactions...

I only have direct experience with ayahuasca shamanism, but for that case, they do have most of those things, as well as demonstrable, and reproducible, curative effects, and have reportedly had them for thousands of years. (Obviously, that last isn't a claim I can very well verify.)

...anyone anywhere can invent a just-so story.

Just so, and I didn't mean to imply that I personally believe the shamans' version of how their medicine works. Regardless of their beliefs, mine, or anyone else's, however, it does; there's no way people would continue to come back, over millennia, to what can be one of the most harrowing experiences I can conceive, if it didn't.

Moreover, there are documented studies, done by genuine lab-coat-wearing scientist types, with measured doses and control groups and everything, that detail its effects, and its unambiguous efficacy. It's only the prevailing sentiment towards psychedelic compounds, and the restrictions on their study that engenders, that have prevented the kind of exploration I think we'd both like to see -- which is the point TFA was making in the first place.

[wdewind]

'1) Just so, and I didn't mean to imply that I personally believe the shamans' version of how their medicine works. Regardless of their beliefs, mine, or anyone else's, however, it does; there's no way people would continue to come back, over millennia, to what can be one of the most harrowing experiences I can conceive, if it didn't.

2) Moreover, there are documented studies, done by genuine lab-coat-wearing scientist types, with measured doses and control groups and everything, that detail its effects, and its unambiguous efficacy. It's only the prevailing sentiment towards psychedelic compounds, and the restrictions on their study that engenders, that have prevented the kind of exploration I think we'd both like to see -- which is the point TFA was making in the first place.'

1) You're talking about a very small number of people, relatively speaking, over a very long period of time, compounded with a lot of mostly second hand, passed down knowledge that has absolutely no recorded data, ie: at best a ton of correlation without causation (correct me if I'm wrong). Humans have been wrong many times before like this, and for just as long, under similar circumstances.

2) You're talking about something very specific, reproducible, and testable. I don't mean to be culturally insensitive, but there is a very real and demonstrably greater value to this kind of information.