[opticalfiber]

Neither Django nor Flask is asynchronous/event loop based. It would neither make sense nor improve performance to run a Django/Flask app on top of uvloop. If you want to develop a web API using uvloop, you should look at aiohttp (http://aiohttp.readthedocs.io/en/stable/).

[eeZi]

Or Tornado, which migrated to the asyncio event loop and is a much more mature alternative.