[aruggirello]

BTW you can run 16-bit Windows apps in Wine under 64-bit Linux, provided your kernel version is <= 3.13, or >= 3.15 and you disable a security enhancement preventing 16-bit code execution by issuing (from root, possibly in your start-up scripts):

  echo 1 > /proc/sys/abi/ldt16

Some 16-bit programs under Wine might also need:

  echo 0 > /proc/sys/vm/mmap_min_addr

Edit: not sure about kernel version 3.14.

[muterad_murilax]

Is it possible to run 16-bit Windows applications in Wine on the Windows Subsystem for Linux?

[swiley]

The "kernel" there is written by Microsoft and is kind of wonky. Stuff like FTDI cables don't even work the way you would expect.